In clinical trials COVID-19 vaccines have been shown to provide excellent protection from getting sick with COVID-19.

The Pfizer vaccine is about 95% effective at preventing symptomatic COVID-19 after two doses.

The AstraZeneca vaccine is about 62% - 73% effective at preventing symptomatic COVID-19 after two doses.1

Both Pfizer and AstraZeneca vaccines have been shown to reduce transmission of COVID-19. Studies from the UK suggest a range between 30% to 47% reduction in transmission to household contacts.1

There is no data to suggest COVID-19 vaccines cause harm for people with chronic liver disease. Vaccines are, in general, less effective in patients with chronic liver disease and those post-liver transplant but there is no data specifically for the COVID-19 vaccines.2


  1. Department of Health. (2021, July 6). COVID-19 vaccination – ATAGI clinical guidance on COVID-19 vaccine in Australia in 2021. Retrieved from Australian Government Department of Health:
  2. British Liver Trust. (2021, April 9). Update for people with liver disease on the COVID-19 vaccine. Retrieved from British Liver Trust:

Updated 14 July 2021